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 TOP TEN ASTRO 2025

1. Phase III randomized trial of proton vs. Photon therapy for patients with non-metastatic breast cancer receiving comprehensive nodal radiation: a radiotherapy comparative effectiveness (radcomp) consortium trial: health-related quality of life outcomes

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2. Primary results for the phase III trial of toxicity reduction using proton beam therapy for oropharyngeal cancer (torpedo; cruk/18/010)

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3. A double-blinded placebo-controlled biomarker stratified randomized trial of apalutamide (apa) and radiotherapy for recurrent prostate cancer (nrg gu006, balance trial)

4. Bladder adjuvant radiotherapy (bart): clinical outcomes from a phase III multicenter randomized controlled trial

5. Tumor treating fields (ttfields) after stereotactic radiosurgery (srs) for brain metastases from non-small cell lung cancer (nsclc bm): final results of the phase 3 metis trial

6. Toxicities and quality of life following observation or radiation therapy for dupuytren's disease in the international depart randomized trial

7. Androgen deprivation therapy (adt) and high dose definitive radiotherapy (rt) +/- whole pelvic rt in patients with unfavorable intermediate or favorable high-risk prostate cancer: early results of a phase III randomized controlled trial

8. Efficacy of hypofractionated stereotactic radiotherapy with different dose fractionation regimens combined with concurrent bevacizumab in recurrent high-grade gliomas: a randomized controlled trial

9. Primary Results from NRG-GU005: A Phase III Trial of SBRT vs. Hypofractionated IMRT for Localized Intermediate Risk Prostate Cancer

10. Comprehensive patient reported outcomes (pros) from nrg lu005: a randomized trial of chemoradiation (crt) +/- atezolizumab in limited-stage small cell lung cancer (ls-sclc)

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