Exploring Factors Associated with Late Urinary Toxicity After Prostate Stereotactic Body Radiotherapy: Findings from the PACE-B Study

Eur Urol. 2026 Jan;89(1):71-79.

https://pubmed.ncbi.nlm.nih.gov/41130825/

 

An international placebo-controlled randomized multicenter trial of nimorazole with accelerated chemo-radiotherapy for locally advanced HPV-negative squamous cell carcinoma of the head and neck (HNSCC)

Radiother Oncol. 2026 Jan;214:111227.

https://pubmed.ncbi.nlm.nih.gov/41138857/

 

Comprehensive radiotherapy quality assurance analysis from individual DICOM data in the HypoG-01 phase 3 trial

Radiother Oncol. 2026 Jan;214:111202.

https://pubmed.ncbi.nlm.nih.gov/41173355/

 

Concurrent and adjuvant temozolomide for 1p/19q non-co-deleted anaplastic glioma (CATNON; EORTC study 26053-22054): final and exploratory analyses of a randomised, open-label, phase 3 trial

Lancet Oncol. 2026 Jan;27(1):45-56. 

https://pubmed.ncbi.nlm.nih.gov/41449147/

 

Molecular profile-based adjuvant treatment for women with high-intermediate risk endometrial cancer (PORTEC-4a): results of a randomised, open-label, phase 3, multicentre, non-inferiority trial

Lancet Oncol. 2026 Jan;27(1):23-35. 

https://pubmed.ncbi.nlm.nih.gov/41449145/

 

HYPofractionated Adjuvant RadioTherapy in 1 Versus 2 Weeks in High-Risk Patients With Breast Cancer (HYPART): Acute Toxicity Results

Int J Radiat Oncol Biol Phys. 2026 Jan 1;124(1):133-146.

https://pubmed.ncbi.nlm.nih.gov/40780546/

 

Late Toxicities and Quality of Life After a Radiation Boost for Breast Ductal Carcinoma In Situ: Boost or No Boost in DCIS Randomized Trial

Int J Radiat Oncol Biol Phys. 2026 Jan 1;124(1):109-121.

https://pubmed.ncbi.nlm.nih.gov/40752655/

 

Nivolumab added to cisplatin and radiotherapy versus cisplatin and radiotherapy alone after surgery for people with squamous cell carcinoma of the head and neck at a high risk of relapse (GORTEC 2018-01 NIVOPOST-OP): a randomised, open-label, phase 3 trial

Lancet. 2026 Jan 24;407(10526):363-374. 

https://pubmed.ncbi.nlm.nih.gov/41448222/

 

Proton versus photon radiotherapy for patients with oropharyngeal cancer in the USA: a multicentre, randomised, open-label, non-inferiority phase 3 trial

Lancet. 2026 Jan 10;407(10524):174-184. 

https://pubmed.ncbi.nlm.nih.gov/41391462/

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Routinely collected health data on 10-year genitourinary and gastrointestinal morbidity after ultra-hypofractionated versus conventionally fractionated radiotherapy for localised prostate cancer in the randomised, non-inferiority, phase 3 trial HYPO-RT-PC

Radiother Oncol. 2026 Feb;215:111323.

https://pubmed.ncbi.nlm.nih.gov/41389860/

 

Twelve-Month Results From the CISTO Study Comparing Radical Cystectomy Versus Bladder-Sparing Therapy for Recurrent High-Grade Non-Muscle-Invasive Bladder Cancer

J Clin Oncol. 2026 Feb;44(4):274-285. 

https://pubmed.ncbi.nlm.nih.gov/41397208/

Tumor Treating Fields Therapy After Stereotactic Radiosurgery for Brain Metastases From Non-Small Cell Lung Cancer: Final Results of the Phase 3 METIS Study

Int J Radiat Oncol Biol Phys. 2026 Feb 1;124(2):278-293. 

https://pubmed.ncbi.nlm.nih.gov/41033612/

 

O-(2-[18F]fluoroethyl)-L-tyrosine-PET-guided versus contrast-enhanced T1-weighted MRI-guided re-irradiation in patients with recurrent glioblastoma (GLIAA/NOA-10 ARO2013-01): a multicentre, open-label, randomised trial

Lancet Oncol. 2026 Feb;27(2):169-180. 

https://pubmed.ncbi.nlm.nih.gov/41429128/

 

Dosimetric and Clinical Effects of Polyethylene Glycol Gel in Radical Concurrent Chemoradiation Therapy for Cervical Cancer: A Phase 3 Prospective Multicenter Randomized Controlled Trial

Int J Radiat Oncol Biol Phys. 2026 Feb 1;124(2):349-358. 

https://pubmed.ncbi.nlm.nih.gov/40876576/

 

Dose-intensified Versus Conventional-dose Salvage Radiotherapy for Biochemically Recurrent Prostate Cancer After Prostatectomy: Long-term Data from the SAKK 09/10 Randomised Phase 3 Trial

Eur Urol. 2026 Mar;89(3):199-203.

https://pubmed.ncbi.nlm.nih.gov/41494929/

 

Three Versus 6 Months of Adjuvant Oxaliplatin-Fluoropyrimidine Chemotherapy for Colorectal Cancer: Final Results of SCOT-An International, Randomized, Phase III, Noninferiority Trial

J Clin Oncol. 2026 Mar;44(7):534-539. 

https://pubmed.ncbi.nlm.nih.gov/41512219/

 

Gemcitabine Intravesical System Plus Cetrelimab or Cetrelimab Alone as Neoadjuvant Therapy in Muscle-Invasive Bladder Cancer: SunRISe-4 Primary Analysis and Biomarker Results

J Clin Oncol. 2026 Mar;44(7):586-597.

https://pubmed.ncbi.nlm.nih.gov/41337691/

 

Chemoradiation ± Atezolizumab in Limited-Stage Small Cell Lung Cancer: Results of NRG Oncology/Alliance LU005

J Clin Oncol. 2026 Mar 10;44(8):630-640.

https://pubmed.ncbi.nlm.nih.gov/41529214/

 

Ultra-hypofractionated versus conventionally fractionated radiotherapy for localised prostate cancer (HYPO-RT-PC): 10-year outcomes of an open-label, randomised, phase 3, non-inferiority trial

Lancet Oncol. 2026 Mar;27(3):293-301. 

https://pubmed.ncbi.nlm.nih.gov/41655576/

 

Toxicities and Quality of Life following Observation or Radiation Therapy for Dupuytren's Disease: Three-Year Secondary Analysis Data From the Prevention Group of the International Dupuytren's Evaluation of Preventative or Adjuvant Radiation Therapy (DEPART) Randomized Trial

Int J Radiat Oncol Biol Phys. 2026 Mar 1;124(3):604-613. 

https://pubmed.ncbi.nlm.nih.gov/41027544/

 

Hypofractionated Dose Escalation Versus Conventionally Fractionated Radiation Therapy for Patients With Intermediate- and High-Risk Localized Prostate Cancer: Long-Term Results of the HYPRO Trial

Int J Radiat Oncol Biol Phys. 2026 Mar 15;124(4):928-936

https://pubmed.ncbi.nlm.nih.gov/41106690/

 

Parotid-Sparing Versus Conventional Whole Brain Radiation Therapy: A Multi-Institutional Randomized Clinical Trial

Int J Radiat Oncol Biol Phys. 2026 Mar 15;124(4):1024-1032. 

https://pubmed.ncbi.nlm.nih.gov/41161645/

 

Effectiveness of Low-Cost Polyurethane Film in Reducing Dermatitis Severity in Breast Cancer Patients With Higher Fitzpatrick Skin Types Undergoing Hypofractionated Irradiation With Simultaneous Integrated Boost: An Intrapatient Randomized Controlled Trial

Int J Radiat Oncol Biol Phys. 2026 Mar 15;124(4):952-960.

https://pubmed.ncbi.nlm.nih.gov/41187861/

 

Simultaneous Integrated Dose Reduction Radiation Therapy Versus Conventional Fractionated Radiation Therapy With Chemotherapy for Limited-Stage Small Cell Lung Cancer in the Modern Treatment Era: A Phase 3, Randomized Clinical Trial (SDR-RT trial)

Int J Radiat Oncol Biol Phys. 2026 Mar 1;124(3):692-701.

https://pubmed.ncbi.nlm.nih.gov/41101556/

 

5-year results of hypofractionated locoregional radiotherapy in early breast cancer HypoG-01 (UNICANCER): a French multicentre, randomised, non-inferiority, phase 3, open-label, controlled trial

Lancet. 2026 Mar 7;407(10532):976-987.

https://pubmed.ncbi.nlm.nih.gov/41794436/

Proton beam therapy for oropharyngeal cancer (TORPEdO): a phase 3, randomised controlled trial

Lancet. 2026 Mar 28;407(10535):1259-1275.

https://pubmed.ncbi.nlm.nih.gov/41875914/

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