The Fraction Size Sensitivity of Late Genitourinary Toxicity: Analysis of Alpha/Beta (α/β) Ratios in the CHHiP Trial.

Int J Radiat Oncol Biol Phys. 2023 Feb 1;115(2):327-336.

Více informací ZDE 

Comparison of short course radiotherapy with chemoradiotherapy for locally advanced rectal cancers in the elderly: A multicentre, randomised, non-blinded, phase 3 trial.

Eur J Cancer. 2023 Feb;180:62-70.

Více informací ZDE 

Mepitel Film for the Prevention of Acute Radiation Dermatitis in Breast Cancer: A Randomized Multicenter Open-Label Phase III Trial.

J Clin Oncol. 2023 Feb 20;41(6):1250-1264.

Více informací ZDE 

Radiosurgery of limited brain metastases from primary solid tumor: results of the randomized phase III trial (NCT02355613) comparing treatments executed with a specialized or a C-arm linac-based platform.

Radiat Oncol. 2023 Feb 7;18(1):28.

Více informací ZDE 

Hyperfractionation compared with standard fractionation in intensity-modulated radiotherapy for patients with locally advanced recurrent nasopharyngeal carcinoma: a multicentre, randomised, open-label, phase 3 trial.

Lancet. 2023 Mar 18;401(10380):917-927.

Více informací ZDE 

Randomized, Multicenter, Phase 3 Study of Accelerated Fraction Radiation Therapy With Concomitant Boost to the Gross Tumor Volume Compared With Conventional Fractionation in Concurrent Chemoradiation in Patients With Unresectable Stage III Non-Small Cell Lung Cancer: The Korean Radiation Oncology Group 09-03 Trial.

Int J Radiat Oncol Biol Phys. 2023 Mar 15;115(4):873-885.

Více informací ZDE 

Accelerated partial breast irradiation using sole interstitial multicatheter brachytherapy compared with whole-breast irradiation with boost for early breast cancer: 10-year results of a GEC-ESTRO randomised, phase 3, non-inferiority trial.

Lancet Oncol. 2023 Mar;24(3):262-272.

Více informací ZDE 

The Fraction Size Sensitivity of Late Genitourinary Toxicity: Analysis of Alpha/Beta (α/β) Ratios in the CHHiP Trial.

Int J Radiat Oncol Biol Phys. 2023 Feb 1;115(2):327-336.

Více informací ZDE 

Comparison of short course radiotherapy with chemoradiotherapy for locally advanced rectal cancers in the elderly: A multicentre, randomised, non-blinded, phase 3 trial.

Eur J Cancer. 2023 Feb;180:62-70.

Více informací ZDE 

Mepitel Film for the Prevention of Acute Radiation Dermatitis in Breast Cancer: A Randomized Multicenter Open-Label Phase III Trial.

J Clin Oncol. 2023 Feb 20;41(6):1250-1264.

Více informací ZDE 

Radiosurgery of limited brain metastases from primary solid tumor: results of the randomized phase III trial (NCT02355613) comparing treatments executed with a specialized or a C-arm linac-based platform.

Radiat Oncol. 2023 Feb 7;18(1):28.

Více informací ZDE 

Hyperfractionation compared with standard fractionation in intensity-modulated radiotherapy for patients with locally advanced recurrent nasopharyngeal carcinoma: a multicentre, randomised, open-label, phase 3 trial.

Lancet. 2023 Mar 18;401(10380):917-927.

Více informací ZDE 

Randomized, Multicenter, Phase 3 Study of Accelerated Fraction Radiation Therapy With Concomitant Boost to the Gross Tumor Volume Compared With Conventional Fractionation in Concurrent Chemoradiation in Patients With Unresectable Stage III Non-Small Cell Lung Cancer: The Korean Radiation Oncology Group 09-03 Trial.

Int J Radiat Oncol Biol Phys. 2023 Mar 15;115(4):873-885.

Více informací ZDE 

Accelerated partial breast irradiation using sole interstitial multicatheter brachytherapy compared with whole-breast irradiation with boost for early breast cancer: 10-year results of a GEC-ESTRO randomised, phase 3, non-inferiority trial.

Lancet Oncol. 2023 Mar;24(3):262-272.

Více informací ZDE 

Neoadjuvant chemoradiotherapy with radiation dose escalation with contact x-ray brachytherapy boost or external beam radiotherapy boost for organ preservation in early cT2-cT3 rectal adenocarcinoma (OPERA): a phase 3, randomised controlled trial.

Lancet Gastroenterol Hepatol. 2023 Apr;8(4):356-367.

Více informací ZDE 

Long-Term Results of a Phase 3 Randomized Prospective Trial of Erectile Tissue-Sparing Intensity-Modulated Radiation Therapy for Men With Clinically Localized Prostate Cancer.

Int J Radiat Oncol Biol Phys. 2023 Apr 1;115(5):1074-1084.

Více informací ZDE 

Cosmetic Results and Side Effects of Accelerated Partial-Breast Irradiation Versus Whole-Breast Irradiation for Low-Risk Invasive Carcinoma of the Breast: The Randomized Phase III IRMA Trial.

J Clin Oncol. 2023 Apr 20;41(12):2201-2210.

Více informací ZDE 

Radiotherapy or Surgery of the Axilla After a Positive Sentinel Node in Breast Cancer: 10-Year Results of the Randomized Controlled EORTC 10981-22023 AMAROS Trial.

J Clin Oncol. 2023 Apr 20;41(12):2159-2165.

Více informací ZDE 

An Updated Analysis of the Survival Endpoints of ASCENDE-RT.

Int J Radiat Oncol Biol Phys. 2023 Apr 1;115(5):1061-1070.

Více informací ZDE 

Adjuvant Osimertinib for Resected EGFR-Mutated Stage IB-IIIA Non-Small-Cell Lung Cancer: Updated Results From the Phase III Randomized ADAURA Trial.

J Clin Oncol. 2023 Apr 1;41(10):1830-1840.

Více informací ZDE 

High-Dose Versus Standard-Dose Intensity-Modulated Radiotherapy With Concurrent Paclitaxel Plus Carboplatin for Patients With Thoracic Esophageal Squamous Cell Carcinoma: A Randomized, Multicenter, Open-Label, Phase 3 Superiority Trial.

Int J Radiat Oncol Biol Phys. 2023 Apr 1;115(5):1129-1137.

Více informací ZDE 

Left Anterior Descending Coronary Artery Radiation Dose Association With All-Cause Mortality in NRG Oncology Trial RTOG 0617.

Int J Radiat Oncol Biol Phys. 2023 Apr 1;115(5):1138-1143.

Více informací ZDE 

High-Dose Once-Daily Thoracic Radiotherapy in Limited-Stage Small-Cell Lung Cancer: CALGB 30610 (Alliance)/RTOG 0538.

J Clin Oncol. 2023 May 1;41(13):2394-2402.

Více informací ZDE 

Adjuvant chemotherapy following chemoradiotherapy as primary treatment for locally advanced cervical cancer versus chemoradiotherapy alone (OUTBACK): an international, open-label, randomised, phase 3 trial.

Lancet Oncol. 2023 May;24(5):468-482.

Více informací ZDE 

Results of Phase III Randomized Trial for Use of Docetaxel as a Radiosensitizer in Patients With Head and Neck Cancer, Unsuitable for Cisplatin-Based Chemoradiation.

J Clin Oncol. 2023 May 1;41(13):2350-2361.

Více informací ZDE 

Dose-Escalated Radiotherapy Alone or in Combination With Short-Term Androgen Deprivation for Intermediate-Risk Prostate Cancer: Results of a Phase III Multi-Institutional Trial.

J Clin Oncol. 2023 Jun 10;41(17):3203-3216.

Více informací ZDE 

Dose-Escalated Radiation Alone or in Combination With Short-Term Total Androgen Suppression for Intermediate-Risk Prostate Cancer: Patient-Reported Outcomes From NRG/Radiation Therapy Oncology Group 0815 Randomized Trial.

J Clin Oncol. 2023 Jun 10;41(17):3217-3224.

Více informací ZDE 

Stereotactic Radiosurgery vs Conventional Radiotherapy for Localized Vertebral Metastases of the Spine: Phase 3 Results of NRG Oncology/RTOG 0631 Randomized Clinical Trial.

JAMA Oncol. 2023 Jun 1;9(6):800-807.

Více informací ZDE 

Voluntary versus mechanically-induced deep inspiration breath-hold for left breast cancer: A randomized controlled trial.

Radiother Oncol. 2023 Jun;183:109598.

Více informací ZDE 

Dose-escalated simultaneous integrated boost radiotherapy in early breast cancer (IMPORT HIGH): a multicentre, phase 3, non-inferiority, open-label, randomised controlled trial.

Lancet. 2023 Jun 24;401(10394):2124-2137.

Více informací ZDE 

Patient-Reported Outcomes During and After Treatment for Locally Advanced Rectal Cancer in the PROSPECT Trial (Alliance N1048).

J Clin Oncol. 2023 Jul 20;41(21):3724-3734.

Více informací ZDE 

Preoperative Treatment of Locally Advanced Rectal Cancer.

N Engl J Med. 2023 Jul 27;389(4):322-334.

Více informací ZDE 

Concurrent chemoradiotherapy followed by adjuvant cisplatin-gemcitabine versus cisplatin-fluorouracil chemotherapy for N2-3 nasopharyngeal carcinoma: a multicentre, open-label, randomised, controlled, phase 3 trial.

Lancet Oncol. 2023 Jul;24(7):798-810.

Více informací ZDE 

Overall Survival with Osimertinib in Resected EGFR-Mutated NSCLC.

N Engl J Med. 2023 Jul 13;389(2):137-147.

Více informací ZDE 

Perioperative Pembrolizumab for Early-Stage Non-Small-Cell Lung Cancer.

N Engl J Med. 2023 Aug 10;389(6):491-503.

Více informací ZDE 

Effect of Brachytherapy With External Beam Radiation Therapy Versus Brachytherapy Alone for Intermediate-Risk Prostate Cancer: NRG Oncology RTOG 0232 Randomized Clinical Trial.

J Clin Oncol. 2023 Aug 20;41(24):4035-4044.

Více informací ZDE 

Artificial intelligence-supported screen reading versus standard double reading in the Mammography Screening with Artificial Intelligence trial (MASAI): a clinical safety analysis of a randomised, controlled, non-inferiority, single-blinded, screening accuracy study.

Lancet Oncol. 2023 Aug;24(8):936-944.

Více informací ZDE 

Dysphagia-optimised intensity-modulated radiotherapy versus standard intensity-modulated radiotherapy in patients with head and neck cancer (DARS): a phase 3, multicentre, randomised, controlled trial.

Lancet Oncol. 2023 Aug;24(8):868-880.

Více informací ZDE 

Weekly Adaptive Radiotherapy vs Standard Intensity-Modulated Radiotherapy for Improving Salivary Function in Patients With Head and Neck Cancer: A Phase 3 Randomized Clinical Trial.

JAMA Oncol. 2023 Aug 1;9(8):1056-1064.

Více informací ZDE 

Radiotherapy for Ledderhose disease: Results of the LedRad-study, a prospective multicentre randomised double-blind phase 3 trial.

Radiother Oncol. 2023 Aug;185:109718.

Více informací ZDE 

Androgen Deprivation and Radiotherapy with or Without Docetaxel for Localized High-risk Prostate Cancer: Long-term Follow-up from the Randomized NRG Oncology RTOG 0521 Trial.

Eur Urol. 2023 Aug;84(2):156-163.

Více informací ZDE 

A Detailed Evaluation of the Effect of Prostate-specific Antigen-based Screening on Morbidity and Mortality of Prostate Cancer: 21-year Follow-up Results of the Rotterdam Section of the European Randomised Study of Screening for Prostate Cancer.

Eur Urol. 2023 Oct;84(4):426-434.

Více informací ZDE 

Conventional versus hypofractionated postmastectomy proton radiotherapy in the USA (MC1631): a randomised phase 2 trial.

Lancet Oncol. 2023 Oct;24(10):1083-1093.

Více informací ZDE 

Comparison of Changes in Pulmonary Function After Stereotactic Body Radiation Therapy Versus Conventional 3-Dimensional Conformal Radiation Therapy for Stage I and IIA Non-Small Cell Lung Cancer: An Analysis of the TROG 09.02 (CHISEL) Phase 3 Trial.

Int J Radiat Oncol Biol Phys. 2023 Oct 1;117(2):378-386.

Více informací ZDE 

Genomic Classifier Performance in Intermediate-Risk Prostate Cancer: Results From NRG Oncology/RTOG 0126 Randomized Phase 3 Trial.

Int J Radiat Oncol Biol Phys. 2023 Oct 1;117(2):370-377.

Více informací ZDE 

Randomized Phase III Study Comparing Neoadjuvant Chemotherapy Followed by Surgery Versus Chemoradiation in Stage IB2-IIB Cervical Cancer: EORTC-55994.

J Clin Oncol. 2023 Nov 10;41(32):5035-5043.

Více informací ZDE 

Relationship Between Baseline Prostate-specific Antigen on Cancer Detection and Prostate Cancer Death: Long-term Follow-up from the European Randomized Study of Screening for Prostate Cancer.

Eur Urol. 2023 Nov;84(5):503-509.

Více informací ZDE 

Sentinel Lymph Node Biopsy vs No Axillary Surgery in Patients With Small Breast Cancer and Negative Results on Ultrasonography of Axillary Lymph Nodes: The SOUND Randomized Clinical Trial.

JAMA Oncol. 2023 Nov 1;9(11):1557-1564.

Více informací ZDE 

Adding Ovarian Suppression to Tamoxifen for Premenopausal Women With Hormone Receptor-Positive Breast Cancer After Chemotherapy: An 8-Year Follow-Up of the ASTRRA Trial.

J Clin Oncol. 2023 Nov 1;41(31):4864-4871.

Více informací ZDE 

Noninferiority of Local Control and Comparable Toxicity of Intensity Modulated Radiation Therapy With Simultaneous Integrated Boost in Breast Cancer: 5-Year Results of the IMRT-MC2 Phase III Trial.

Int J Radiat Oncol Biol Phys. 2023 Nov 15;117(4):857-868.

Více informací ZDE 

Sustained Preservation of Cognition and Prevention of Patient-Reported Symptoms With Hippocampal Avoidance During Whole-Brain Radiation Therapy for Brain Metastases: Final Results of NRG Oncology CC001.

Int J Radiat Oncol Biol Phys. 2023 Nov 1;117(3):571-580.

Více informací ZDE 

Salvage Radiation Therapy After Radical Prostatectomy: Analysis of Toxicity by Dose-Fractionation in the RADICALS-RT Trial.

Int J Radiat Oncol Biol Phys. 2023 Nov 1;117(3):624-629.

Více informací ZDE 

Reducing Target Volumes of Intensity Modulated Radiation Therapy After Induction Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma: Long-Term Results of a Prospective, Multicenter, Randomized Trial.

Int J Radiat Oncol Biol Phys. 2023 Nov 15;117(4):914-924.

Více informací ZDE 

Durvalumab versus placebo with chemoradiotherapy for locally advanced cervical cancer (CALLA): a randomised, double-blind, phase 3 trial.

Lancet Oncol. 2023 Dec;24(12):1334-1348.

Více informací ZDE 

Long-Term Follow-up of a Randomized Controlled Trial on Accelerated Radiation Therapy Versus Standard Fractionated Radiation Therapy for Early Glottic Cancer (JCOG0701A3).

Int J Radiat Oncol Biol Phys. 2023 Dec 1;117(5):1118-1124.

Více informací ZDE 

Explainable Artificial Intelligence to Identify Dosimetric Predictors of Toxicity in Patients with Locally Advanced Non-Small Cell Lung Cancer: A Secondary Analysis of RTOG 0617.

Int J Radiat Oncol Biol Phys. 2023 Dec 1;117(5):1287-1296.

Více informací ZDE 

Interpretable Machine Learning for Choosing Radiation Dose-volume Constraints on Cardio-pulmonary Substructures Associated with Overall Survival in NRG Oncology RTOG 0617.

Int J Radiat Oncol Biol Phys. 2023 Dec 1;117(5):1270-1286.

Více informací ZDE 

1