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Randomizované studie 2018

Late normal tissue effects in the arm and shoulder following lymphatic radiotherapy: Results from the UK START (Standardisation of Breast Radiotherapy) trials.

Radiother Oncol. 2018 Jan;126(1):155-162.

Více informací ZDE 

Treatment outcomes after reduction of the target volume of intensity-modulated radiotherapyfollowing induction chemotherapy in patients with locoregionally advanced nasopharyngealcarcinoma: A prospective, multi-center, randomized clinical trial.

Radiother Oncol. 2018 Jan;126(1):37-42.

Více informací ZDE 

The potential benefits from respiratory gating for breast cancer patients regarding target coverage and dose to organs at risk when applying strict dose limits to the heart: results from the DBCG HYPO trial.

Acta Oncol. 2018 Jan;57(1):113-119.

Více informací ZDE 

Effect of Neoadjuvant Chemoradiotherapy on Health-Related Quality of Life in Esophageal or Junctional Cancer: Results From the Randomized CROSS Trial.

J Clin Oncol. 2018 Jan 20;36(3):268-275.

Více informací ZDE 

R-CHOP 14 with or without radiotherapy in nonbulky limited-stage diffuse large B-cell lymphoma.

Blood. 2018 Jan 11;131(2):174-181.

Více informací ZDE 

Patterns of locoregional failure in locally advanced non-small cell lung cancer treated with definitive conformal radiotherapy: Results from the Gating 2006 trial.

Radiother Oncol. 2018 Feb;126(2):291-299.

Více informací ZDE 

Long-term quality of life in inoperable non-small cell lung cancer patients treated with conventionally fractionated compared to hyperfractionated accelerated radiotherapy - Results of the randomized CHARTWEL trial.

Radiother Oncol. 2018 Feb;126(2):283-290.

Více informací ZDE 

Radiotherapy for prostate cancer - Does daily image guidance with tighter margins improve patient reported outcomes compared to weekly orthogonal verified irradiation? Results from a randomized controlled trial.

Radiother Oncol. 2018 Feb;126(2):229-235.

Více informací ZDE 

Impact of dose intensified salvage radiation therapy on urinary continence recovery after radical prostatectomy: Results of the randomized trial SAKK 09/10.

Radiother Oncol. 2018 Feb;126(2):257-262.

Více informací ZDE 

Randomized, Double-Blind, Placebo-Controlled Trial of Shuanghua Baihe Tablets to Prevent Oral Mucositis in Patients With Nasopharyngeal Cancer Undergoing Chemoradiation Therapy.

Int J Radiat Oncol Biol Phys. 2018 Feb 1;100(2):418-426.

Více informací ZDE 

4 Weeks Versus 5 Weeks of Hypofractionated High-dose Radiation Therapy as Primary Therapy for Prostate Cancer: Interim Safety Analysis of a Randomized Phase 3 Trial.

Int J Radiat Oncol Biol Phys. 2018 Mar 15;100(4):866-870.

Více informací ZDE 

NRG oncology RTOG 9006: a phase III randomized trial of hyperfractionated radiotherapy (RT) and BCNU versus standard RT and BCNU for malignant glioma patients.

J Neurooncol. 2018 Mar;137(1):39-47.

Více informací ZDE 

Adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): final results of an international, open-label, multicentre, randomised, phase 3 trial. 

Lancet Oncol. 2018 Mar;19(3):295-309.

Více informací ZDE 

DAHANCA 10 - Effect of darbepoetin alfa and radiotherapy in the treatment of squamous cell carcinoma of the head and neck. A multicenter, open-label, randomized, phase 3 trial by the Danish head and neck cancer group. 

Radiother Oncol. 2018 Apr;127(1):12-19.

Více informací ZDE 

Concurrent chemoradiotherapy with nedaplatin versus cisplatin in stage II-IVB nasopharyngeal carcinoma: an open-label, non-inferiority, randomised phase 3 trial. 

Lancet Oncol. 2018 Apr;19(4):461-473.

Více informací ZDE 

Once-a-Week Versus Once-Every-3-Weeks Cisplatin Chemoradiation for Locally Advanced Head and Neck Cancer: A Phase III Randomized Noninferiority Trial. 

J Clin Oncol. 2018 Apr 10;36(11):1064-1072.

Více informací ZDE 

Standard whole prostate gland radiotherapy with and without lesion boost in prostate cancer: Toxicity in the FLAME randomized controlled trial. 

Radiother Oncol. 2018 Apr;127(1):74-80.

Více informací ZDE 

Comparison of 36 Gy, 20 Gy, or No Radiation Therapy After 6 Cycles of EBVP Chemotherapy and Complete Remission in Early-Stage Hodgkin Lymphoma Without Risk Factors: Results of the EORT-GELA H9-F Intergroup Randomized Trial.

Int J Radiat Oncol Biol Phys. 2018 Apr 1;100(5):1133-1145.

Více informací ZDE 

Radiotherapy quality assurance for the RTOG 0834/EORTC 26053-22054/NCIC CTG CEC.1/CATNON intergroup trial "concurrent and adjuvant temozolomide chemotherapy in newly diagnosed non-1p/19q deleted anaplastic glioma": Individual case review analysis. 

Radiother Oncol. 2018 May;127(2):292-298.

Více informací ZDE 

Chemotherapy versus chemoradiotherapy after surgery and preoperative chemotherapy for resectable gastric cancer (CRITICS): an international, open-label, randomised phase 3 trial. 

Lancet Oncol. 2018 May;19(5):616-628.

Více informací ZDE 

Postoperative Concurrent Chemoradiotherapy Versus Postoperative Radiotherapy in High-Risk Cutaneous Squamous Cell Carcinoma of the Head and Neck: The Randomized Phase III TROG 05.01 Trial. 

J Clin Oncol. 2018 May 1;36(13):1275-1283.

Více informací ZDE 

Quality-of-life results for accelerated partial breast irradiation with interstitial brachytherapy versus whole-breast irradiation in early breast cancer after breast-conserving surgery (GEC-ESTRO): 5-year results of a randomised, phase 3 trial. 

Lancet Oncol. 2018 Jun;19(6):834-844.

Více informací ZDE 

Neoadjuvant Chemotherapy Followed by Radical Surgery Versus Concomitant Chemotherapy and Radiotherapy in Patients With Stage IB2, IIA, or IIB Squamous Cervical Cancer: A Randomized Controlled Trial.

J Clin Oncol. 2018 Jun 1;36(16):1548-1555.

Více informací ZDE 

Preoperative radiotherapy or chemoradiotherapy in rectal cancer - Is survival improved? An update of the "Nordic" LARC study in non-resectable cancers. 

Radiother Oncol. 2018 Jun;127(3):392-395.

Více informací ZDE 

A Randomized Trial of Mometasone Furoate 0.1% to Reduce High-Grade Acute Radiation Dermatitis in Breast Cancer Patients Receiving Postmastectomy Radiation. 

Int J Radiat Oncol Biol Phys. 2018 Jun 1;101(2):325-333.

Více informací ZDE 

A Randomized Comparison of Radiation Therapy Techniques in the Management of Node-Positive Breast Cancer: Primary Outcomes Analysis.  NEW

Int J Radiat Oncol Biol Phys. 2018 Aug 1;101(5):1149-1158.

Více informací ZDE 

Bevacizumab Monotherapy Reduces Radiation-induced Brain Necrosis in Nasopharyngeal Carcinoma Patients: A Randomized Controlled Trial.  NEW

Int J Radiat Oncol Biol Phys. 2018 Aug 1;101(5):1087-1095.

Více informací ZDE 

Concurrent-Adjuvant Chemoradiation Therapy for Stage III-IVB Nasopharyngeal Carcinoma-Exploration for Achieving Optimal 10-Year Therapeutic Ratio.  NEW

Int J Radiat Oncol Biol Phys. 2018 Aug 1;101(5):1078-1086.

Více informací ZDE 

Late toxicity in the randomized multicenter HYPRO trial for prostate cancer analyzed with automated treatment planning.  NEW

Radiother Oncol. 2018 Aug;128(2):349-356.

Více informací ZDE 

Patient-Reported Toxicity During Pelvic Intensity-Modulated Radiation Therapy: NRG Oncology-RTOG 1203.  NEW

J Clin Oncol. 2018 Aug 20;36(24):2538-2544.

Více informací ZDE 

Predictors for poor cosmetic outcome in patients with early stage breast cancer treated with breast conserving therapy: Results of the Young boost trial.  NEW

Radiother Oncol. 2018 Sep;128(3):434-441.

Více informací ZDE 

Final results of a randomized phase III trial of induction chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in patients with stage IVA and IVB nasopharyngeal carcinoma-Taiwan Cooperative Oncology Group (TCOG) 1303 Study.  NEW

Ann Oncol. 2018 Sep 1;29(9):1972-1979.

Více informací ZDE 

Chemoradiotherapy in Elderly Patients With Non-Small-Cell Lung Cancer: Long-Term Follow-Up of a Randomized Trial (JCOG0301).  NEW

Clin Lung Cancer. 2018 Sep;19(5):e619-e627.

Více informací ZDE 

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