Effect of Pregabalin on Radiotherapy-Related Neuropathic Pain in Patients With Head and Neck Cancer: A Randomized Controlled Trial.

J Clin Oncol. 2019 Jan 10;37(2):135-143.

Více informací ZDE 

Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial.

Lancet. 2019 Jan 5;393(10166):51-60.

Více informací ZDE 

Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial.

Lancet. 2019 Jan 5;393(10166):40-50.

Více informací ZDE 

Patient-Reported Outcomes Over 5 Years After Whole- or Partial-Breast Radiotherapy: Longitudinal Analysis of the IMPORT LOW (CRUK/06/003) Phase III Randomized Controlled Trial.

J Clin Oncol. 2019 Feb 1;37(4):305-317.

Více informací ZDE 

Moderate Hypofractionation in Intermediate- and High-Risk, Localized Prostate Cancer: Health-Related Quality of Life From the Randomized, Phase 3 HYPRO Trial.

Int J Radiat Oncol Biol Phys. 2019 Mar 15;103(4):823-833.

Více informací ZDE 

Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA-09): a randomised, open-label, phase 3 trial.

Lancet. 2019 Feb 16;393(10172):678-688.

Více informací ZDE 

Hypofractionated versus conventional fractionated postmastectomy radiotherapy for patients with high-risk breast cancer: a randomised, non-inferiority, open-label, phase 3 trial.

Lancet Oncol. 2019 Mar;20(3):352-360.

Více informací ZDE 

Effect of Doxepin Mouthwash or Diphenhydramine-Lidocaine-Antacid Mouthwash vs Placebo on Radiotherapy-Related Oral Mucositis Pain: The Alliance A221304 Randomized Clinical Trial.

JAMA. 2019 Apr 16;321(15):1481-1490.

Více informací ZDE 

Stereotactic ablative radiotherapy versus standard radiotherapy in stage 1 non-small-cell lung cancer (TROG 09.02 CHISEL): a phase 3, open-label, randomised controlled trial.

Lancet Oncol. 2019 Apr;20(4):494-503.

Více informací ZDE 

The INTERACT Trial: Long-term results of a randomised trial on preoperative capecitabine-based radiochemotherapy intensified by concomitant boost or oxaliplatin, for cT2 (distal)-cT3 rectal cancer.

Radiother Oncol. 2019 May;134:110-118.

Více informací ZDE 

Prophylactic Irradiation of Tracts in Patients With Malignant Pleural Mesothelioma: An Open-Label, Multicenter, Phase III Randomized Trial.

J Clin Oncol. 2019 May 10;37(14):1200-1208.

Více informací ZDE 

Effect of Chemotherapy With Docetaxel With Androgen Suppression and Radiotherapy for Localized High-Risk Prostate Cancer: The Randomized Phase III NRG Oncology RTOG 0521 Trial.

J Clin Oncol. 2019 May 10;37(14):1159-1168.

Více informací ZDE 

Adjuvant Chemotherapy plus Radiation for Locally Advanced Endometrial Cancer.

N Engl J Med. 2019 Jun 13;380(24):2317-2326.

Více informací ZDE 

Phase III Trial: Adjuvant Pelvic Radiation Therapy Versus Vaginal Brachytherapy Plus Paclitaxel/Carboplatin in High-Intermediate and High-Risk Early Stage Endometrial Cancer.

J Clin Oncol. 2019 Jul 20;37(21):1810-1818.

Více informací ZDE 

Concurrent chemoradiotherapy with/without induction chemotherapy in locoregionally advancednasopharyngeal carcinoma: Long-term results of phase 3 randomized controlled trial.

Int J Cancer. 2019 Jul 1;145(1):295-305.

Více informací ZDE 

Comparing Paclitaxel Plus Fluorouracil Versus Cisplatin Plus Fluorouracil in Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Cancer: A Randomized, Multicenter, Phase III Clinical Trial.

J Clin Oncol. 2019 Jul 10;37(20):1695-1703.

Více informací ZDE 

HOPON (Hyperbaric Oxygen for the Prevention of Osteoradionecrosis): A Randomized Controlled Trial of Hyperbaric Oxygen to Prevent Osteoradionecrosis of the Irradiated Mandible After Dentoalveolar Surgery.

Int J Radiat Oncol Biol Phys. 2019 Jul 1;104(3):530-539.

Více informací ZDE 

Dose Escalation for Prostate Adenocarcinoma: A Long-Term Update on the Outcomes of a Phase 3, Single Institution Randomized Clinical Trial.

Int J Radiat Oncol Biol Phys. 2019 Jul 15;104(4):790-797.

Více informací ZDE 

A prospective, three-arm, randomized trial of EGCG for preventing radiation-induced esophagitis in lung cancer patients receiving radiotherapy.

Radiother Oncol. 2019 Aug;137:186-191.

Více informací ZDE 

Ultra-hypofractionated versus conventionally fractionated radiotherapy for prostate cancer: 5-year outcomes of the HYPO-RT-PC randomised, non-inferiority, phase 3 trial.

Lancet. 2019 Aug 3;394(10196):385-395.

Více informací ZDE 

Induction chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in locoregionally advanced nasopharyngeal carcinoma: long-term results of a phase III multicentre randomised controlled trial.

Eur J Cancer. 2019 Sep;119:87-96.

Více informací ZDE 

Gemcitabine and Cisplatin Induction Chemotherapy in Nasopharyngeal Carcinoma.

N Engl J Med. 2019 Sep 19;381(12):1124-1135.

Více informací ZDE 

A single-blind, randomised controlled trial of StrataXRT® - A silicone-based film-forming gel dressing for prophylaxis and management of radiation dermatitis in patients with head and neck cancer.

Radiother Oncol. 2019 Oct;139:72-78.

Více informací ZDE 

A randomized trial (RAREST-01) comparing Mepitel® Film and standard care for prevention of radiation dermatitis in patients irradiated for locally advanced squamous cell carcinoma of the head-and-neck (SCCHN).

Radiother Oncol. 2019 Oct;139:79-82.

Více informací ZDE 

Intensity-modulated fractionated radiotherapy versus stereotactic body radiotherapy for prostate cancer (PACE-B): acute toxicity findings from an international, randomised, open-label, phase 3, non-inferiority trial.

Lancet Oncol. 2019 Nov;20(11):1531-1543.

Více informací ZDE 

Final Analysis of DeCOG-SLT Trial: No Survival Benefit for Complete Lymph Node Dissection in Patients With Melanoma With Positive Sentinel Node.

J Clin Oncol. 2019 Nov 10;37(32):3000-3008.

Více informací ZDE 

Postoperative adjuvant IMRT for patients with HCC and portal vein tumor thrombus: An open-label randomized controlled trial.

Radiother Oncol. 2019 Nov;140:20-25.

Více informací ZDE 

Health-related quality of life after prophylactic cranial irradiation for stage III non-small cell lung cancer patients: Results from the NVALT-11/DLCRG-02 phase III study.

Radiother Oncol. 2019 Nov 13;144:65-71.

Více informací ZDE 

Does A Longer Waiting Period After Neoadjuvant Radio-chemotherapy Improve the Oncological Prognosis of Rectal Cancer?: Three Years' Follow-up Results of the Greccar-6 Randomized Multicenter Trial.

Ann Surg. 2019 Nov;270(5):747-754.

Více informací ZDE 

Adjuvant Whole-Brain Radiation Therapy Compared With Observation After Local Treatment of Melanoma Brain Metastases: A Multicenter, Randomized Phase III Trial.

J Clin Oncol. 2019 Nov 20;37(33):3132-3141.

Více informací ZDE 

Positron Emission Tomography-Guided Treatment in Early-Stage Favorable Hodgkin Lymphoma: Final Results of the International, Randomized Phase III HD16 Trial by the German Hodgkin Study Group.

J Clin Oncol. 2019 Nov 1;37(31):2835-2845.

Více informací ZDE 

Quality of Life Outcomes After Stereotactic Ablative Radiation Therapy (SABR) Versus Standard of Care Treatments in the Oligometastatic Setting: A Secondary Analysis of the SABR-COMET Randomized Trial.

Int J Radiat Oncol Biol Phys. 2019 Dec 1;105(5):943-947.

Více informací ZDE 

Neoadjuvant Modified FOLFOX6 With or Without Radiation Versus Fluorouracil Plus Radiation for Locally Advanced Rectal Cancer: Final Results of the Chinese FOWARC Trial.

J Clin Oncol. 2019 Dec 1;37(34):3223-3233.

Více informací ZDE 

Short-term androgen deprivation therapy combined with radiotherapy as salvage treatment after radical prostatectomy for prostate cancer (GETUG-AFU 16): a 112-month follow-up of a phase 3, randomised trial.

Lancet Oncol. 2019 Dec;20(12):1740-1749.

Více informací ZDE 

Long-term primary results of accelerated partial breast irradiation after breast-conserving surgery for early-stage breast cancer: a randomised, phase 3, equivalence trial.

Lancet. 2019 Dec 14;394(10215):2155-2164.

Více informací ZDE 

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